InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP1CA

Summary

InnateDB Protein

IDBP-602944.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP1CA

Protein Name

protein phosphatase 1, catalytic subunit, alpha isozyme

Synonyms

PP-1A; PP1A; PP1alpha; PPP1A;

Species

Homo sapiens

Ensembl Protein

ENSP00000431146

InnateDB Gene

IDBG-60210 (PPP1CA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 355 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	355 [view]
Protein-Protein	352 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0016787	hydrolase activity

Biological Process

GO:0016311	dephosphorylation
GO:0045087	innate immune response (InnateDB)

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR029052 Metallo-dependent phosphatase-like

PFAM

PF00149

PRINTS

PR00114

PIRSF

SMART

SM00156

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt