InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SRP54

Summary

InnateDB Protein

IDBP-603512.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SRP54

Protein Name

signal recognition particle 54kDa

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000451775

InnateDB Gene

IDBG-4659 (SRP54)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.

Experimentally validated
Total	29 [view]
Protein-Protein	26 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0008312	7S RNA binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006614	SRP-dependent cotranslational protein targeting to membrane

Cellular Component

GO:0048500

signal recognition particle

Protein Structure and Domains

PDB ID

InterPro

IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain
IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain
IPR003495 CobW/HypB/UreG domain
IPR003593 AAA+ ATPase domain
IPR004125 Signal recognition particle, SRP54 subunit, M-domain
IPR006325 Signal recognition particle, SRP54 subunit, eukaryotic
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR029007 MobB-type P-loop domain

PFAM

PF00448
PF01656
PF02492
PF02978
PF03205

PRINTS

PIRSF

SMART

SM00962
SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite