InnateDB Protein
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IDBP-604019.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ASCL3
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Protein Name
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achaete-scute complex homolog 3 (Drosophila)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000435770
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InnateDB Gene
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IDBG-31041 (ASCL3)
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Protein Structure
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Function |
Transcriptional repressor. Inhibits myogenesis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
Widely expressed in fetal and adult tissues. {ECO:0000269PubMed:15475265}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
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InterPro |
IPR011598
Myc-type, basic helix-loop-helix (bHLH) domain
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PFAM |
PF00010
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PRINTS |
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PIRSF |
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SMART |
SM00353
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TIGRFAMs |
|
Modification |
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SwissProt |
Q9NQ33
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PhosphoSite |
PhosphoSite-Q9NQ33
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
56676
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UniGene |
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RefSeq |
NP_065697
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HUGO |
HGNC:740
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OMIM |
609154
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CCDS |
CCDS7795
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HPRD |
18523
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IMGT |
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EMBL |
AB046450
AJ400877
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GenPept |
BAB83913
CAB92288
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