Version 5.4
Homo sapiens Gene: ASCL3
Summary
InnateDB Gene IDBG-31041.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASCL3
Gene Name achaete-scute complex homolog 3 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176009
Encoded Proteins
IDBP-604019
achaete-scute complex homolog 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:8937579-8938211
Strand Reverse strand
Band p15.4
Transcripts
ENST00000531618 ENSP00000435770
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035951
View Gene Order
ENSBTAG00000032339
Not yet available
Cross-References
SwissProt Q9NQ33
TrEMBL
UniProt Splice Variant
Entrez Gene 56676
UniGene
RefSeq NM_020646
HUGO HGNC:740
OMIM 609154
CCDS CCDS7795
HPRD
IMGT
EMBL AB046450 AJ400877
GenPept BAB83913 CAB92288
RNA Seq Atlas 56676

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca