Version 5.4
Homo sapiens Protein: EIF4G2
Summary
InnateDB Protein IDBP-604112.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF4G2
Protein Name eukaryotic translation initiation factor 4 gamma, 2
Synonyms AAG1; DAP5; NAT1; P97;
Species Homo sapiens
Ensembl Protein ENSP00000433664
InnateDB Gene IDBG-31984 (EIF4G2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 38 [view]
Protein-Protein 38 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003307 W2 domain
IPR003890 MIF4G-like, type 3
IPR003891 Initiation factor eIF-4 gamma, MA3
IPR016024 Armadillo-type fold
PFAM PF02020
PF02854
PF02847
PRINTS
PIRSF
SMART SM00515
SM00543
SM00544
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q59G42
UniProt Splice Variant
Entrez Gene 1982
UniGene Hs.183684
RefSeq NP_001166176
HUGO HGNC:3297
OMIM 602325
CCDS CCDS31428
HPRD 09084
IMGT
EMBL AB209267 AC116535 AK302886 AY513274 BC065276 CH471064
GenPept AAH65276 AAT08027 BAD92504 BAG64064 EAW68552 EAW68553 EAW68555

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca