InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GAL

Summary

InnateDB Protein

IDBP-61519.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GAL

Protein Name

galanin prepropeptide

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000265643

InnateDB Gene

IDBG-61517 (GAL)

Protein Structure

UniProt Annotation

Function

Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005179	hormone activity
GO:0005184	neuropeptide hormone activity
GO:0005515	protein binding
GO:0031764	type 1 galanin receptor binding
GO:0031765	type 2 galanin receptor binding
GO:0031766	type 3 galanin receptor binding

Biological Process

GO:0006954	inflammatory response
GO:0007218	neuropeptide signaling pathway
GO:0007399	nervous system development
GO:0007631	feeding behavior
GO:0008285	negative regulation of cell proliferation
GO:0010737	protein kinase A signaling
GO:0019933	cAMP-mediated signaling
GO:0030073	insulin secretion
GO:0031943	regulation of glucocorticoid metabolic process
GO:0032868	response to insulin
GO:0035902	response to immobilization stress
GO:0042493	response to drug
GO:0043065	positive regulation of apoptotic process
GO:0043627	response to estrogen
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050672	negative regulation of lymphocyte proliferation
GO:0051464	positive regulation of cortisol secretion
GO:0051795	positive regulation of catagen
GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
GO:1902891	negative regulation of root hair elongation

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0030141	secretory granule
GO:0043025	neuronal cell body