Version 5.4
Mus musculus Protein: Panx1
Summary
InnateDB Protein IDBP-620314.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Panx1
Protein Name pannexin 1
Synonyms AI847747;
Species Mus musculus
Ensembl Protein ENSMUSP00000132764
InnateDB Gene IDBG-134948 (Panx1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002020 protease binding
GO:0003779 actin binding
GO:0005102 receptor binding
GO:0005262 calcium channel activity
GO:0015267 channel activity
GO:0022840 leak channel activity
GO:0044325 ion channel binding
GO:0046982 protein heterodimerization activity
GO:0051015 actin filament binding
GO:0055077 gap junction hemi-channel activity
GO:0097110 scaffold protein binding
Biological Process
GO:0002931 response to ischemia
GO:0007267 cell-cell signaling
GO:0033198 response to ATP
GO:0034214 protein hexamerization
GO:0050715 positive regulation of cytokine secretion
GO:0050717 positive regulation of interleukin-1 alpha secretion
GO:0050718 positive regulation of interleukin-1 beta secretion
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0032059 bleb
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:1860055
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PY07
UniProt Splice Variant
Entrez Gene 55991
UniGene Mm.142253
RefSeq
MGI ID
MGI Symbol Panx1
OMIM
CCDS
HPRD
IMGT
EMBL AC154295
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca