InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lats2

Summary

InnateDB Protein

IDBP-620334.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lats2

Protein Name

large tumor suppressor 2

Synonyms

4932411G09Rik; AV277261; AW228608;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000134142

InnateDB Gene

IDBG-168883 (Lats2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0007067	mitotic nuclear division
GO:0030216	keratinocyte differentiation
GO:0034613	cellular protein localization
GO:0035329	hippo signaling
GO:0046620	regulation of organ growth
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1354386

InterPro

IPR000719 Protein kinase domain
IPR011009 Protein kinase-like domain

PFAM

PF00069

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UYM3

UniProt Splice Variant

Entrez Gene

50523

UniGene

Mm.408428

RefSeq

MGI ID

MGI Symbol

Lats2

OMIM

CCDS

HPRD

IMGT

EMBL

AC154504

GenPept