Mus musculus Protein: Tbc1d24 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-621036.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Tbc1d24 | ||||||
Protein Name | TBC1 domain family, member 24 | ||||||
Synonyms | |||||||
Species | Mus musculus | ||||||
Ensembl Protein | ENSMUSP00000127005 | ||||||
InnateDB Gene | IDBG-145425 (Tbc1d24) | ||||||
Protein Structure |
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UniProt Annotation | |||||||
Function | May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function. {ECO:0000269PubMed:20727515}. | ||||||
Subcellular Localization | Cytoplasm {ECO:0000250}. Note=Partially expressed at the plasma membrane. {ECO:0000250}. | ||||||
Disease Associations | |||||||
Tissue Specificity | Expressed in brain, particularly at the level of the cortex and the hippocampus. Expressed in the inner ear in spiral ganglion cells, a collection of neurons critical for hearing and balance. {ECO:0000269PubMed:20727515, ECO:0000269PubMed:24387994}. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | MGI:2443456 | ||||||
InterPro |
IPR000195
Rab-GTPase-TBC domain IPR006571 TLDc |
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PFAM |
PF00566
PF07534 |
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PRINTS | |||||||
PIRSF | |||||||
SMART |
SM00164
SM00584 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q3UUG6 | ||||||
PhosphoSite | PhosphoSite-Q3UUG6 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 224617 | ||||||
UniGene | Mm.301585 | ||||||
RefSeq | NP_001157319 | ||||||
MGI ID | |||||||
MGI Symbol | Tbc1d24 | ||||||
OMIM | |||||||
CCDS | CCDS50012 | ||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AK049306 AK049754 AK083833 AK084693 AK086293 AK129304 AK138431 AK147647 AK161054 BC080845 BC094417 | ||||||
GenPept | AAH80845 AAH94417 BAC33671 BAC33904 BAC39035 BAC39255 BAC39644 BAC98114 BAE23659 BAE28046 BAE36174 | ||||||