Mus musculus Gene: Tbc1d24
Summary
InnateDB Gene IDBG-145425.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d24
Gene Name TBC1 domain family, member 24
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036473
Encoded Proteins
TBC1 domain family, member 24
TBC1 domain family, member 24
TBC1 domain family, member 24
TBC1 domain family, member 24
TBC1 domain family, member 24
TBC1 domain family, member 24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162065:
This gene encodes a protein with a conserved domain, referred to as the TBC domain, characteristic of proteins which interact with GTPases. TBC domain proteins may serve as GTPase-activating proteins for a particular group of GTPases, the Rab (Ras-related proteins in brain) small GTPases which are involved in the regulation of membrane trafficking. Mutations in this gene are associated with familial infantile myoclonic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:24175431-24205562
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000040474 ENSMUSP00000036458
ENSMUST00000097376 ENSMUSP00000094989
ENSMUST00000168410 ENSMUSP00000128868
ENSMUST00000171189 ENSMUSP00000128001
ENSMUST00000168378 ENSMUSP00000126107
ENSMUST00000167791 ENSMUSP00000127005
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q3UUG6
TrEMBL
UniProt Splice Variant
Entrez Gene 224617
UniGene Mm.301585
RefSeq NM_001163847 NM_001163848 NM_001163849 NM_001163850 NM_001163851 NM_001163852 NM_001163853 NM_173186
OMIM
CCDS CCDS28477 CCDS50012
HPRD
IMGT
MGI ID MGI:2443456
MGI Symbol Tbc1d24
EMBL AK049306 AK049754 AK083833 AK084693 AK086293 AK129304 AK138431 AK147647 AK161054 BC080845 BC094417
GenPept AAH80845 AAH94417 BAC33671 BAC33904 BAC39035 BAC39255 BAC39644 BAC98114 BAE23659 BAE28046 BAE36174
RNA Seq Atlas 224617