Version 5.4
Mus musculus Protein: Wac
Summary
InnateDB Protein IDBP-621240.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wac
Protein Name WW domain containing adaptor with coiled-coil
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000131032
InnateDB Gene IDBG-128123 (Wac)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000993 RNA polymerase II core binding
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0010390 histone monoubiquitination
GO:0016239 positive regulation of macroautophagy
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0044783 G1 DNA damage checkpoint
GO:0045893 positive regulation of transcription, DNA-templated
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination
Cellular Component
GO:0005681 spliceosomal complex
Protein Structure and Domains
PDB ID MGI:2387357
InterPro IPR001202 WW domain
PFAM PF00397
PRINTS
PIRSF
SMART SM00456
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q6U6
UniProt Splice Variant
Entrez Gene 225131
UniGene Mm.490814
RefSeq
MGI ID
MGI Symbol Wac
OMIM
CCDS
HPRD
IMGT
EMBL AC130718 AC147624
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca