Version 5.4
Mus musculus Protein: Abca7
Summary
InnateDB Protein IDBP-621646.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abca7
Protein Name ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms Abc51; ABCX;
Species Mus musculus
Ensembl Protein ENSMUSP00000128121
InnateDB Gene IDBG-171979 (Abca7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0005548 phospholipid transporter activity
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0034188 apolipoprotein A-I receptor activity
Biological Process
GO:0006200 ATP catabolic process
GO:0017121 phospholipid scrambling
GO:0032780 negative regulation of ATPase activity
GO:0032781 positive regulation of ATPase activity
GO:0033344 cholesterol efflux
GO:0033700 phospholipid efflux
GO:0034380 high-density lipoprotein particle assembly
GO:0038027 apolipoprotein A-I-mediated signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016324 apical plasma membrane
Protein Structure and Domains
PDB ID MGI:1351646
InterPro IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00005
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q6G4
UniProt Splice Variant
Entrez Gene 27403
UniGene Mm.103351
RefSeq XP_006513773
MGI ID
MGI Symbol Abca7
OMIM
CCDS
HPRD
IMGT
EMBL AC151846 AC161120
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca