InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pafah1b2

Summary

InnateDB Protein

IDBP-621873.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pafah1b2

Protein Name

platelet-activating factor acetylhydrolase, isoform 1b, subunit 2

Synonyms

AI747451; AU021353; mus[b]; Pafahb;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127851

InnateDB Gene

IDBG-160930 (Pafah1b2)

Protein Structure

UniProt Annotation

Function

Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0005515	protein binding
GO:0016788	hydrolase activity, acting on ester bonds
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006629	lipid metabolic process
GO:0006928	cellular component movement
GO:0007283	spermatogenesis
GO:0007420	brain development
GO:0016042	lipid catabolic process
GO:0016239	positive regulation of macroautophagy