InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Idh1

Summary

InnateDB Protein

IDBP-622177.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Idh1

Protein Name

isocitrate dehydrogenase 1 (NADP+), soluble

Synonyms

AI314845; AI788952; E030024J03Rik; Id-1; Idh-1; Idpc;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127307

InnateDB Gene

IDBG-162070 (Idh1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004450	isocitrate dehydrogenase (NADP+) activity
GO:0005102	receptor binding
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803	protein homodimerization activity
GO:0050661	NADP binding
GO:0051287	NAD binding

Biological Process

GO:0006097	glyoxylate cycle
GO:0006099	tricarboxylic acid cycle
GO:0006102	isocitrate metabolic process
GO:0006103	2-oxoglutarate metabolic process
GO:0006749	glutathione metabolic process
GO:0006979	response to oxidative stress
GO:0008585	female gonad development
GO:0048545	response to steroid hormone
GO:0055114	oxidation-reduction process