Version 5.4
Mus musculus Protein: Nrxn1
Summary
InnateDB Protein IDBP-622712.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nrxn1
Protein Name neurexin I
Synonyms 1700062G21Rik; 9330127H16Rik; A230068P09Rik; mKIAA0578;
Species Mus musculus
Ensembl Protein ENSMUSP00000133724
InnateDB Gene IDBG-201803 (Nrxn1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005246 calcium channel regulator activity
GO:0005515 protein binding
GO:0033130 acetylcholine receptor binding
Biological Process
GO:0007268 synaptic transmission
GO:0007269 neurotransmitter secretion
GO:0007416 synapse assembly
GO:0051965 positive regulation of synapse assembly
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0090129 positive regulation of synapse maturation
Cellular Component
GO:0016021 integral component of membrane
GO:0042734 presynaptic membrane
Protein Structure and Domains
PDB ID MGI:1096391
InterPro IPR001791 Laminin G domain
IPR003585 Neurexin/syndecan/glycophorin C
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00054
PF02210
PRINTS
PIRSF
SMART SM00210
SM00282
SM00294
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UXK2
UniProt Splice Variant
Entrez Gene 18189
UniGene Mm.312068
RefSeq XP_006523881
MGI ID
MGI Symbol Nrxn1
OMIM
CCDS
HPRD
IMGT
EMBL AC101872 AC131326 AC151286 AC154325 AC154599 AC167814 AC170901 AC171209 CT025708 CT486002
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca