InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndrg1

Summary

InnateDB Protein

IDBP-622850.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndrg1

Protein Name

N-myc downstream regulated gene 1

Synonyms

CAP43; CMT4D; DRG1; HMSNL; Ndr1; Ndrl; NMSL; PROXY1; RTP; TDD5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130584

InnateDB Gene

IDBG-146853 (Ndrg1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 73 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	73 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008017	microtubule binding
GO:0017137	Rab GTPase binding
GO:0043015	gamma-tubulin binding
GO:0045296	cadherin binding

Biological Process

GO:0030330	DNA damage response, signal transduction by p53 class mediator
GO:0045576	mast cell activation
GO:0071456	cellular response to hypoxia
GO:0090232	positive regulation of spindle checkpoint

Cellular Component

GO:0005634	nucleus
GO:0005813	centrosome
GO:0005874	microtubule
GO:0005886	plasma membrane
GO:0005913	cell-cell adherens junction
GO:0048471	perinuclear region of cytoplasm
GO:0055038	recycling endosome membrane

Protein Structure and Domains

PDB ID

MGI:1341799

InterPro

IPR004142 NDRG
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF03096

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q5I8

UniProt Splice Variant

Entrez Gene

17988

UniGene

Mm.30837

RefSeq

MGI ID

MGI Symbol

Ndrg1

OMIM

CCDS

HPRD

IMGT

EMBL

AC087116 AC107859

GenPept