InnateDB Protein
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IDBP-623884.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hmg20b
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Protein Name
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high mobility group 20 B
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Synonyms
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AW610687; BRAF35; Hmgx2; Hmgxb2; Smarce1r;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000128807
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InnateDB Gene
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IDBG-178149 (Hmg20b)
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Protein Structure
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Function |
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00267}. Chromosome {ECO:0000250}. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed in adult tissues, particularly kidney, skin, testis and uterus. Highly expressed in embryonic tissues with high mitotic index, such as the proliferating ventricular zones of the fore-, mid- and hindbrain.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1341190
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InterPro |
IPR009071
High mobility group box domain
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PFAM |
PF00505
PF09011
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PRINTS |
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PIRSF |
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SMART |
SM00398
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Z104
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PhosphoSite |
PhosphoSite-Q9Z104
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TrEMBL |
Q3U1Z7
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UniProt Splice Variant |
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Entrez Gene |
15353
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UniGene |
Mm.38474
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RefSeq |
XP_006513313
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MGI ID |
2CRJ
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MGI Symbol |
Hmg20b
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OMIM |
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CCDS |
CCDS24055
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HPRD |
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IMGT |
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EMBL |
AC155937
AF067430
AF146224
AK153816
AK155615
AK155890
AL355734
AL355735
BC003924
BC011334
CH466553
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GenPept |
AAD15897
AAF66708
AAH03924
AAH11334
BAE32194
BAE33346
BAE33486
CAB90813
CAB90814
EDL31421
EDL31424
EDL31425
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