InnateDB Protein
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IDBP-624011.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pkig
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Protein Name
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protein kinase inhibitor, gamma
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Synonyms
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PKIgamma;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000126223
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InnateDB Gene
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IDBG-211949 (Pkig)
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Protein Structure
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Function |
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004862
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cAMP-dependent protein kinase inhibitor activity
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Biological Process |
GO:0000122
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negative regulation of transcription from RNA polymerase II promoter
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GO:0006469
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negative regulation of protein kinase activity
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GO:0007165
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signal transduction
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GO:0042308
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negative regulation of protein import into nucleus
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GO:0071901
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negative regulation of protein serine/threonine kinase activity
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Cellular Component |
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PDB ID |
MGI:1343086
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InterPro |
IPR004171
cAMP-dependent protein kinase inhibitor
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PFAM |
PF02827
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PRINTS |
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PIRSF |
PIRSF001667
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O70139
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q3TP50
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UniProt Splice Variant |
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Entrez Gene |
18769
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UniGene |
Mm.415944
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RefSeq |
NP_001157527
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MGI ID |
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MGI Symbol |
Pkig
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OMIM |
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CCDS |
CCDS17014
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HPRD |
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IMGT |
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EMBL |
AK164716
AK168614
AL591490
BC026550
CH466551
U97170
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GenPept |
AAC09065
AAH26550
BAE37887
BAE40480
EDL06344
EDL06345
EDL06348
EDL06349
EDL06350
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