InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Racgap1

Summary

InnateDB Protein

IDBP-624683.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Racgap1

Protein Name

Rac GTPase-activating protein 1

Synonyms

AI227039; AI327394; Band25; gtl11; GTPase; MgcRacGAP; mKIAA1478;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130876

InnateDB Gene

IDBG-183510 (Racgap1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008017	microtubule binding
GO:0019901	protein kinase binding
GO:0043014	alpha-tubulin binding
GO:0043015	gamma-tubulin binding
GO:0048487	beta-tubulin binding

Biological Process

GO:0000281	mitotic cytokinesis
GO:0000915	cytokinesis, actomyosin contractile ring assembly
GO:0007108	cytokinesis, initiation of separation
GO:0007283	spermatogenesis
GO:0008272	sulfate transport
GO:0032467	positive regulation of cytokinesis
GO:0043547	positive regulation of GTPase activity
GO:0051256	spindle midzone assembly involved in mitosis
GO:0051988	regulation of attachment of spindle microtubules to kinetochore

Cellular Component

GO:0005634	nucleus
GO:0030496	midbody
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
GO:0032154	cleavage furrow
GO:0051233	spindle midzone
GO:0097149	centralspindlin complex

Protein Structure and Domains

PDB ID

MGI:1349423

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q9N9

UniProt Splice Variant

Entrez Gene

26934

UniGene

Mm.412372

RefSeq

MGI ID

MGI Symbol

Racgap1

OMIM

CCDS

HPRD

IMGT

EMBL

AC139317

GenPept