Mus musculus Protein: Hsd17b3
Summary
InnateDB Protein IDBP-625075.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hsd17b3
Protein Name hydroxysteroid (17-beta) dehydrogenase 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000132011
InnateDB Gene IDBG-161411 (Hsd17b3)
Protein Structure
UniProt Annotation
Function Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
GO:0061370 testosterone biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID MGI:107177
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
PFAM PF00106
PRINTS PR00080
PR00081
PIRSF PIRSF000126
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70385
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 15487
UniGene Mm.5109
RefSeq NP_032317
MGI ID
MGI Symbol Hsd17b3
OMIM
CCDS CCDS26594
HPRD
IMGT
EMBL CH466631 CT009717 U66827
GenPept AAB06793 EDL16224