Version 5.4
| Mus musculus Gene: Hsd17b3 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-161411.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Hsd17b3 | ||||||
| Gene Name | hydroxysteroid (17-beta) dehydrogenase 3 | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000033122 | ||||||
| Encoded Proteins |
hydroxysteroid (17-beta) dehydrogenase 3
hydroxysteroid (17-beta) dehydrogenase 3
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130948:
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008] This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 13:64058274-64089201 | ||||||
| Strand | Reverse strand | ||||||
| Band | B3 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Androgen biosynthesis pathway
Metabolism of steroid hormones and vitamin D pathway
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| KEGG |
Steroid hormone biosynthesis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Androgen biosynthesis pathway
Synthesis of very long-chain fatty acyl-CoAs pathway
Fatty Acyl-CoA Biosynthesis pathway
Triglyceride Biosynthesis pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism of steroid hormones and vitamin D pathway
Metabolism pathway
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| KEGG |
Steroid hormone biosynthesis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | P70385 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 15487 | ||||||
| UniGene | Mm.5109 | ||||||
| RefSeq | NM_008291 | ||||||
| OMIM | |||||||
| CCDS | CCDS26594 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:107177 | ||||||
| MGI Symbol | Hsd17b3 | ||||||
| EMBL | CH466631 CT009717 U66827 | ||||||
| GenPept | AAB06793 EDL16224 | ||||||
| RNA Seq Atlas | 15487 | ||||||