InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lrrc4c

Summary

InnateDB Protein

IDBP-625415.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lrrc4c

Protein Name

leucine rich repeat containing 4C

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000131795

InnateDB Gene

IDBG-193102 (Lrrc4c)

Protein Structure

UniProt Annotation

Function

May promote neurite outgrowth of developing thalamic neurons. {ECO:0000269PubMed:14595443}.

Subcellular Localization

Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0050770

regulation of axonogenesis

Cellular Component

GO:0005615	extracellular space
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

MGI:2442636

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM