InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mocs1

Summary

InnateDB Protein

IDBP-625561.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mocs1

Protein Name

molybdenum cofactor synthesis 1

Synonyms

3110045D15Rik; AI043170; AW536397;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133694

InnateDB Gene

IDBG-190104 (Mocs1)

Protein Structure

UniProt Annotation

Function

Isoform Mocs1a and isoform Mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005525	GTP binding
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding
GO:0061597	cyclic pyranopterin monophosphate synthase activity

Biological Process

GO:0006777	Mo-molybdopterin cofactor biosynthetic process
GO:0032324	molybdopterin cofactor biosynthetic process

Cellular Component

GO:0005575	cellular_component
GO:0019008	molybdopterin synthase complex

Protein Structure and Domains

PDB ID

MGI:1928904

InterPro

IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain
IPR006638 Elongator protein 3/MiaB/NifB
IPR007197 Radical SAM
IPR010505 Molybdenum cofactor synthesis C-terminal
IPR013483 Molybdenum cofactor biosynthesis protein A
IPR023045 Molybdenum cofactor biosynthesis C

PFAM

PF01967
PF04055
PF06463

PRINTS

PIRSF

SMART

SM00729

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5RKZ7