Version 5.4
Mus musculus Protein: Gp1bb
Summary
InnateDB Protein IDBP-625757.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gp1bb
Protein Name glycoprotein Ib, beta polypeptide
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000126292
InnateDB Gene IDBG-142031 (Gp1bb)
Protein Structure
UniProt Annotation
Function Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium. {ECO:0000250}.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007155 cell adhesion
GO:0007596 blood coagulation
Cellular Component
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID MGI:107852
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
PFAM PF01462
PF01463
PRINTS
PIRSF
SMART SM00013
SM00082
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P56400
PhosphoSite PhosphoSite-P56400
TrEMBL
UniProt Splice Variant
Entrez Gene 14724
UniGene
RefSeq NP_034457
MGI ID
MGI Symbol Gp1bb
OMIM
CCDS CCDS49787
HPRD
IMGT
EMBL AB001419
GenPept BAA22424

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca