InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Chd2

Summary

InnateDB Protein

IDBP-626969.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Chd2

Protein Name

chromodomain helicase DNA binding protein 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126352

InnateDB Gene

IDBG-266633 (Chd2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001046	core promoter sequence-specific DNA binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0042393	histone binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006974	cellular response to DNA damage stimulus
GO:0007517	muscle organ development
GO:0016568	chromatin modification
GO:0060218	hematopoietic stem cell differentiation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:2448567

InterPro

IPR000330 SNF2-related
IPR000953 Chromo domain/shadow
IPR001650 Helicase, C-terminal
IPR009057 Homeodomain-like
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR016197 Chromo domain-like
IPR023780 Chromo domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271
PF00385

PRINTS

PIRSF

SMART

SM00298
SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

E9PZM4