Version 5.4
Mus musculus Gene: Chd2
Summary
InnateDB Gene IDBG-266633.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chd2
Gene Name chromodomain helicase DNA binding protein 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000078671
Encoded Proteins
IDBP-192779
chromodomain helicase DNA binding protein 2
IDBP-626969
chromodomain helicase DNA binding protein 2
IDBP-626975
chromodomain helicase DNA binding protein 2
IDBP-626978
chromodomain helicase DNA binding protein 2
IDBP-722811
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173575:
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:73426691-73541746
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000038366
ENSMUST00000026895 ENSMUSP00000026895
ENSMUST00000169922 ENSMUSP00000126352
ENSMUST00000173785 ENSMUSP00000133714
ENSMUST00000172704 ENSMUSP00000134484
ENSMUST00000181971 ENSMUSP00000137985
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001046 core promoter sequence-specific DNA binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042393 histone binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0007517 muscle organ development
GO:0016568 chromatin modification
GO:0060218 hematopoietic stem cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173575
View Gene Order
ENSBTAG00000017776
Not yet available
Cross-References
SwissProt E9PZM4
TrEMBL Q3V177
UniProt Splice Variant
Entrez Gene 244059
UniGene Mm.34955
RefSeq NM_001081345
OMIM
CCDS CCDS52274
HPRD
IMGT
MGI ID MGI:2448567
MGI Symbol Chd2
EMBL AC099699 AC154883 AK132638
GenPept BAE21274
RNA Seq Atlas 244059

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca