InnateDB Protein
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IDBP-627280.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Lax1
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Protein Name
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lymphocyte transmembrane adaptor 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000131126
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InnateDB Gene
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IDBG-221584 (Lax1)
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Protein Structure
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Function |
Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. {ECO:0000269PubMed:15843560}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in T-cells and B-cells. {ECO:0000269PubMed:15843560}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2443362
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BHB3
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PhosphoSite |
PhosphoSite-Q8BHB3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
240754
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UniGene |
Mm.36534
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RefSeq |
NP_766430
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MGI ID |
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MGI Symbol |
Lax1
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OMIM |
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CCDS |
CCDS35711
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HPRD |
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IMGT |
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EMBL |
AK040834
AK088503
AY090785
BC042765
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GenPept |
AAH42765
AAM09819
BAC30715
BAC40394
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