InnateDB Protein
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IDBP-627813.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ebf4
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Protein Name
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early B-cell factor 4
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000133528
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InnateDB Gene
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IDBG-206321 (Ebf4)
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Protein Structure
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Function |
Seems to weakly activate transcription. Binds an Olf-1 consensus site in vitro.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed in the neuronal and basal cell layers of olfactory epithelium. Absent in the vomeronasal organ. {ECO:0000269PubMed:12139918}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
1
[view]
|
DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
Accession |
GO Term |
GO:0000977
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RNA polymerase II regulatory region sequence-specific DNA binding
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GO:0001228
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RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0003677
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DNA binding
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GO:0005515
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protein binding
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GO:0008134
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transcription factor binding
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GO:0046872
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metal ion binding
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GO:0046983
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protein dimerization activity
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0007275
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multicellular organismal development
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
MGI:2385972
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InterPro |
IPR002909
IPT domain
IPR014756
Immunoglobulin E-set
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PFAM |
PF01833
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PRINTS |
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PIRSF |
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SMART |
SM00429
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K4J2
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
228598
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UniGene |
Mm.483929
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RefSeq |
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MGI ID |
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MGI Symbol |
Ebf4
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AF387630
AF387631
AF387632
AF387633
AF387634
BX890605
BX936285
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GenPept |
AAM97580
AAM97581
AAM97582
AAM97583
AAM97584
CAM15942
CAM20114
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