Version 5.4
Mus musculus Protein: Ssb
Summary
InnateDB Protein IDBP-627925.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ssb
Protein Name Sjogren syndrome antigen B
Synonyms SS-B;
Species Mus musculus
Ensembl Protein ENSMUSP00000130313
InnateDB Gene IDBG-177350 (Ssb)
Protein Structure
UniProt Annotation
Function Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 44 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID MGI:98423
InterPro IPR000504 RNA recognition motif domain
IPR002344 Lupus La protein
IPR006630 RNA-binding protein Lupus La
IPR014886 RNA-binding motif
PFAM PF00076
PF05383
PF08777
PRINTS PR00302
PIRSF
SMART SM00360
SM00715
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P32067
PhosphoSite PhosphoSite-P32067
TrEMBL Q564E6
UniProt Splice Variant
Entrez Gene 20823
UniGene Mm.487097
RefSeq NP_033304
MGI ID
MGI Symbol Ssb
OMIM
CCDS CCDS16101
HPRD
IMGT
EMBL AK032940 AK088650 AK141487 AL845261 AL929249 BC003820 BC106150 BX322634 CH466519 L00993 Y07951
GenPept AAA39415 AAH03820 AAI06151 BAC28092 BAC40478 BAE24699 CAA69249 EDL27049 EDL27050

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca