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InnateDB Protein
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IDBP-62805.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FLT3LG
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Protein Name
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fms-related tyrosine kinase 3 ligand
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Synonyms
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FL; FLT3L;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000204637
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InnateDB Gene
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IDBG-62803 (FLT3LG)
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Protein Structure
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| Function |
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
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| Subcellular Localization |
Isoform 1: Cell membrane; Single-pass type I membrane protein.Isoform 2: Secreted.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
3
[view]
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| Protein-Protein |
3
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR004213
Flt3 ligand
IPR009079
Four-helical cytokine-like, core
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| PFAM |
PF02947
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
2323
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| UniGene |
Hs.734589
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| RefSeq |
NP_001265567
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| HUGO |
HGNC:3766
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| OMIM |
600007
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| CCDS |
CCDS62753
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| HPRD |
02477
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4