InnateDB Protein
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IDBP-6420.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IL2RB
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Protein Name
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interleukin 2 receptor, beta
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Synonyms
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CD122; IL15RB; P70-75;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000216223
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InnateDB Gene
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IDBG-6418 (IL2RB)
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Protein Structure
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|
Function |
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
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Subcellular Localization |
Membrane; Single-pass type I membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
48
[view]
|
Protein-Protein |
44
[view]
|
Protein-DNA |
4
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
6 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003961
Fibronectin, type III
|
PFAM |
PF00041
PF01108
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PRINTS |
|
PIRSF |
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SMART |
SM00060
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TIGRFAMs |
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Modification |
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SwissProt |
P14784
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PhosphoSite |
PhosphoSite-P14784
|
TrEMBL |
B0QYC2
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UniProt Splice Variant |
|
Entrez Gene |
3560
|
UniGene |
Hs.474787
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RefSeq |
NP_000869
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HUGO |
HGNC:6009
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OMIM |
146710
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CCDS |
CCDS13942
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HPRD |
00896
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IMGT |
|
EMBL |
AF517934
AK312860
AL022314
BC025691
CH471095
CR456506
M26062
Z82188
|
GenPept |
AAA59143
AAH25691
AAM54040
BAG35712
CAA18444
CAG30392
EAW60144
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