Version 5.4
Homo sapiens Protein: RALY
Summary
InnateDB Protein IDBP-67498.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RALY
Protein Name RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
Synonyms HNRPCL2; P542;
Species Homo sapiens
Ensembl Protein ENSP00000364255
InnateDB Gene IDBG-67496 (RALY)
Protein Structure
UniProt Annotation
Function Probable-RNA binding protein. Could be a heterogeneous nuclear ribonucleoprotein (hnRNP). May be involved in pre-mRNA splicing (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 71 experimentally validated interaction(s) in this database.
Experimentally validated
Total 71 [view]
Protein-Protein 70 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0071013 catalytic step 2 spliceosome
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR017347 Heterogeneous nuclear ribonucleoprotein C, Raly
PFAM PF00076
PRINTS
PIRSF PIRSF037992
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKM9
PhosphoSite PhosphoSite-Q9UKM9
TrEMBL Q5QPM2
UniProt Splice Variant
Entrez Gene 22913
UniGene Hs.136947
RefSeq NP_031393
HUGO HGNC:15921
OMIM 614663
CCDS CCDS13229
HPRD 11480
IMGT
EMBL AF148457 AL031668 AL034549 BC105018 L38696
GenPept AAC28898 AAF04487 AAI05019 CAB43742 CAI22150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca