Version 5.4
Bos taurus Protein: GRB10
Summary
InnateDB Protein IDBP-680147.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRB10
Protein Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022720
InnateDB Gene IDBG-628761 (GRB10)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005070 SH3/SH2 adaptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0042326 negative regulation of phosphorylation
GO:0046325 negative regulation of glucose import
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0048009 insulin-like growth factor receptor signaling pathway
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000159 Ras-association
IPR000980 SH2 domain
IPR001849 Pleckstrin homology domain
IPR015042 BPS (Between PH and SH2) domain
IPR029071 Ubiquitin-related domain
PFAM PF00788
PF00017
PF14633
PF00169
PF08947
PRINTS PR00401
PIRSF
SMART SM00314
SM00252
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6U8D5
UniProt Splice Variant
Entrez Gene 407210
UniGene Bt.24356
RefSeq NP_001179515
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY376067 DAAA02009673
GenPept AAR04852

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca