InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SCTR

Summary

InnateDB Protein

IDBP-68044.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SCTR

Protein Name

secretin receptor

Synonyms

SR;

Species

Homo sapiens

Ensembl Protein

ENSP00000019103

InnateDB Gene

IDBG-68042 (SCTR)

Protein Structure

UniProt Annotation

Function

This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0015055	secretin receptor activity

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007586	digestion
GO:0007588	excretion

Cellular Component

GO:0005881	cytoplasmic microtubule
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000832 GPCR, family 2, secretin-like
IPR001771 GPCR, family 2, vasoactive intestinal peptide receptor 1
IPR001879 GPCR, family 2, extracellular hormone receptor domain
IPR002144 GPCR, family 2, secretin receptor
IPR017981 GPCR, family 2-like

PFAM

PF00002
PF02793

PRINTS

PR00249
PR01154
PR00490

PIRSF

SMART

SM00008

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt