Version 5.4
Bos taurus Protein: BRF2
Summary
InnateDB Protein IDBP-680458.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRF2
Protein Name Transcription factor IIIB 50 kDa subunit
Synonyms ZFP36L2;
Species Bos taurus
Ensembl Protein ENSBTAP00000039624
InnateDB Gene IDBG-629066 (BRF2)
Protein Structure
UniProt Annotation
Function General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Predicted by orthology
Total 52 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR013137 Zinc finger, TFIIB-type
IPR013763 Cyclin-like
PFAM PF08271
PRINTS
PIRSF
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q29S07
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 512789
UniGene Bt.37205
RefSeq NP_001015582
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113270 BT020651 BT020781 BT020876 BT020884 BT020898
GenPept AAI13271 AAX08668 AAX08798 AAX08893 AAX08901 AAX08915

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca