Version 5.4
Bos taurus Gene: BRF2
Summary
InnateDB Gene IDBG-629066.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRF2
Gene Name Transcription factor IIIB 50 kDa subunit
Synonyms ZFP36L2
Species Bos taurus
Ensembl Gene ENSBTAG00000027665
Encoded Proteins
IDBP-680458
Transcription factor IIIB 50 kDa subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104221:
This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 27:32799190-32803514
Strand Reverse strand
Band
Transcripts
ENSBTAT00000039838 ENSBTAP00000039624
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Predicted by orthology
Total 52 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104221
View Gene Order
ENSMUSG00000031487
View Gene Order
Pathways
NETPATH
REACTOME
REACT_216178
RNA Polymerase III Transcription pathway
REACT_203707
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_226022
Gene Expression pathway
REACT_212144
RNA Polymerase III Transcription Initiation pathway
REACT_209748
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_221998
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_571
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_233104
RNA Polymerase III Transcription Initiation pathway
REACT_261233
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_233572
Gene Expression pathway
REACT_237241
RNA Polymerase III Transcription pathway
REACT_240508
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q29S07
TrEMBL
UniProt Splice Variant
Entrez Gene 512789
UniGene Bt.37205
RefSeq NM_001015582
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113270 BT020651 BT020781 BT020876 BT020884 BT020898
GenPept AAI13271 AAX08668 AAX08798 AAX08893 AAX08901 AAX08915
RNA Seq Atlas 512789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca