Version 5.4
| Bos taurus Protein: KLHL13 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-680890.2 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | KLHL13 | ||||||||||
| Protein Name | Kelch-like protein 13 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Protein | ENSBTAP00000000639 | ||||||||||
| InnateDB Gene | IDBG-629488 (KLHL13) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis (By similarity). {ECO:0000250}. | ||||||||||
| Subcellular Localization | |||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | |||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR000210
BTB/POZ-like IPR006652 Kelch repeat type 1 IPR011333 BTB/POZ fold IPR011498 Kelch repeat type 2 IPR011705 BTB/Kelch-associated IPR013069 BTB/POZ IPR017096 Kelch-like protein, gigaxonin type |
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| PFAM |
PF01344
PF07646 PF07707 PF00651 |
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| PRINTS | |||||||||||
| PIRSF |
PIRSF037037
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| SMART |
SM00225
SM00612 SM00875 |
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | A6QQY2 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 528138 | ||||||||||
| UniGene | Bt.16194 | ||||||||||
| RefSeq | NP_001095981 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BC150039 | ||||||||||
| GenPept | AAI50040 | ||||||||||