InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HK1

Summary

InnateDB Protein

IDBP-680931.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HK1

Protein Name

hexokinase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016432

InnateDB Gene

IDBG-629484 (HK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004340	glucokinase activity
GO:0004396	hexokinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008865	fructokinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0019158	mannokinase activity

Biological Process

GO:0001678	cellular glucose homeostasis
GO:0005975	carbohydrate metabolic process
GO:0006096	glycolytic process
GO:0016310	phosphorylation
GO:0046835	carbohydrate phosphorylation
GO:0051156	glucose 6-phosphate metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0005929	cilium
GO:0045121	membrane raft
GO:0097228	sperm principal piece

Protein Structure and Domains

PDB ID

InterPro

IPR001312 Hexokinase
IPR022672 Hexokinase, N-terminal
IPR022673 Hexokinase, C-terminal

PFAM

PF00349
PF03727

PRINTS

PR00475

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8SQ77

UniProt Splice Variant

Entrez Gene

280817

UniGene

Bt.66043

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AF542053 AH011529 BC151301 DAAA02061833 DAAA02061834

GenPept

AAI51302 AAL87545 AAQ11378