Bos taurus Protein: GHR
Summary
InnateDB Protein IDBP-681108.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GHR
Protein Name growth hormone receptor precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000001758
InnateDB Gene IDBG-629685 (GHR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0004903 growth hormone receptor activity
GO:0005515 protein binding
GO:0017046 peptide hormone binding
GO:0019838 growth factor binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0019221 cytokine-mediated signaling pathway
GO:0031623 receptor internalization
GO:0032355 response to estradiol
GO:0032870 cellular response to hormone stimulus
GO:0040018 positive regulation of multicellular organism growth
GO:0044236 multicellular organismal metabolic process
GO:0046898 response to cycloheximide
GO:0048009 insulin-like growth factor receptor signaling pathway
GO:0060396 growth hormone receptor signaling pathway
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019898 extrinsic component of membrane
GO:0043235 receptor complex
GO:0070195 growth hormone receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
IPR015152 Growth hormone/erythropoietin receptor, ligand binding
PFAM PF00041
PF01108
PF09067
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6DUF3
UniProt Splice Variant
Entrez Gene 280805
UniGene Bt.79147
RefSeq NP_788781
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03001528 AAFC03001530 AAFC03033137 AAFC03033138 AAFC03033139 AAFC03033140 AAFC03033141 AAFC03034555 AAFC03042485 AAFC03042486 AAFC03119051 AY643807 DQ168854 DQ168855 DQ168856 DQ168857 DQ168860 EU747321 JQ711177
GenPept AAT65182 ABA70591 ABA70592 ABA70593 ABA70594 ABA70597 ACE62925 AFN44371