Version 5.4
Bos taurus Protein: GLO1
Summary
InnateDB Protein IDBP-681835.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLO1
Protein Name lactoylglutathione lyase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000016884
InnateDB Gene IDBG-630387 (GLO1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004462 lactoylglutathione lyase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0008152 metabolic process
GO:0030316 osteoclast differentiation
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain
IPR004361 Glyoxalase I
IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
PFAM PF00903
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A4FUZ1
UniProt Splice Variant
Entrez Gene 540335
UniGene Bt.7760
RefSeq NP_001076965
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123482 DAAA02055011
GenPept AAI23483

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca