Version 5.4
Bos taurus Protein: FCER1A
Summary
InnateDB Protein IDBP-682247.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCER1A
Protein Name high affinity immunoglobulin epsilon receptor subunit alpha
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000017127
InnateDB Gene IDBG-630768 (FCER1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019767 IgE receptor activity
GO:0019863 IgE binding
Biological Process
GO:0000187 activation of MAPK activity
GO:0001812 positive regulation of type I hypersensitivity
GO:0001820 serotonin secretion
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007257 activation of JUN kinase activity
GO:0019370 leukotriene biosynthetic process
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0043306 positive regulation of mast cell degranulation
GO:0045401 positive regulation of interleukin-3 biosynthetic process
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850 positive regulation of calcium-mediated signaling
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
Protein Structure and Domains
PDB ID
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6QQQ4
UniProt Splice Variant
Entrez Gene 506783
UniGene Bt.27043
RefSeq NP_001093780
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149946 DAAA02007004
GenPept AAI49947

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca