Version 5.4
Bos taurus Protein: CD36
Summary
InnateDB Protein IDBP-682791.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD36
Protein Name Platelet glycoprotein 4
Synonyms GPIIIB; GPIV; PAS-4;
Species Bos taurus
Ensembl Protein ENSBTAP00000023750
InnateDB Gene IDBG-631266 (CD36)
Protein Structure
UniProt Annotation
Function Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. {ECO:0000269PubMed:1697855}.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0007155 cell adhesion
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002159 CD36 antigen
IPR005428 Adhesion molecule CD36
PFAM PF01130
PRINTS PR01609
PR01610
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P26201
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281052
UniGene Bt.43948
RefSeq NP_776435
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103112 D45364 X91503
GenPept AAI03113 BAA08224 CAA62803

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca