InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ARHGEF11

Summary

InnateDB Protein

IDBP-682844.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARHGEF11

Protein Name

Rho guanine nucleotide exchange factor (GEF) 11

Synonyms

ARHGEF11;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000055453

InnateDB Gene

IDBG-631202 (ARHGEF11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005089	Rho guanyl-nucleotide exchange factor activity

Biological Process

GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0032321	positive regulation of Rho GTPase activity
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction
GO:0038032	termination of G-protein coupled receptor signaling pathway
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000219 Dbl homology (DH) domain
IPR000342 Regulator of G protein signalling domain
IPR001849 Pleckstrin homology domain
IPR015212 Regulator of G protein signalling-like domain
IPR016137 Regulator of G protein signalling superfamily

PFAM

PF00621
PF00615
PF00169
PF09128

PRINTS

PR01301

PIRSF

SMART

SM00325
SM00233
SM00315

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt