InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DCTN1

Summary

InnateDB Protein

IDBP-682877.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DCTN1

Protein Name

dynactin subunit 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000006430

InnateDB Gene

IDBG-631341 (DCTN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 75 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	75 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016740	transferase activity
GO:0045502	dynein binding
GO:0048037	cofactor binding

Biological Process

GO:0010970	microtubule-based transport
GO:0032402	melanosome transport

Cellular Component

GO:0000776	kinetochore
GO:0000922	spindle pole
GO:0005813	centrosome
GO:0005869	dynactin complex
GO:0005874	microtubule
GO:0016020	membrane
GO:0031252	cell leading edge
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000938 CAP Gly-rich domain
IPR015083 Polyketide synthase, docking domain
IPR022157 Dynein associated protein
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF01302
PF08990
PF12455

PRINTS

PIRSF

SMART

SM01052

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite