Version 5.4
Bos taurus Protein: TNFAIP1
Summary
InnateDB Protein IDBP-683100.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNFAIP1
Protein Name tumor necrosis factor, alpha-induced protein 1 (endothelial)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000010671
InnateDB Gene IDBG-631555 (TNFAIP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0017049 GTP-Rho binding
Biological Process
GO:0006955 immune response
GO:0009790 embryo development
GO:0016477 cell migration
GO:0035024 negative regulation of Rho protein signal transduction
GO:0043149 stress fiber assembly
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0031463 Cul3-RING ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
PFAM PF02214
PF00651
PRINTS
PIRSF
SMART SM00225
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BLB2
UniProt Splice Variant
Entrez Gene 539674
UniGene Bt.29035
RefSeq NP_001179219
HUGO HGNC:11894
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048600
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca