Version 5.4
Bos taurus Protein: DMRT1
Summary
InnateDB Protein IDBP-683226.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DMRT1
Protein Name doublesex and mab-3 related transcription factor 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000023667
InnateDB Gene IDBG-631673 (DMRT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000902 cell morphogenesis
GO:0002176 male germ cell proliferation
GO:0003006 developmental process involved in reproduction
GO:0006355 regulation of transcription, DNA-templated
GO:0007283 spermatogenesis
GO:0008354 germ cell migration
GO:0008584 male gonad development
GO:0030238 male sex determination
GO:0045835 negative regulation of meiosis
GO:0045840 positive regulation of mitosis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046661 male sex differentiation
GO:0048599 oocyte development
GO:0060008 Sertoli cell differentiation
GO:0060009 Sertoli cell development
GO:0060903 positive regulation of meiosis I
GO:1900107 regulation of nodal signaling pathway
GO:2000020 positive regulation of male gonad development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001275 DM DNA-binding domain
IPR022114 Doublesex- and mab-3-related transcription factor 1-like
PFAM PF00751
PF12374
PRINTS
PIRSF
SMART SM00301
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H9KUV0
UniProt Splice Variant
Entrez Gene 616245
UniGene Bt.50653
RefSeq NP_001071528
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02022773 DAAA02022774 DAAA02022775 DAAA02022776
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca