Bos taurus Protein: FOXO3
Summary
InnateDB Protein IDBP-683314.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOXO3
Protein Name forkhead box O3
Synonyms FOXO-3;
Species Bos taurus
Ensembl Protein ENSBTAP00000014920
InnateDB Gene IDBG-631758 (FOXO3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.
Predicted by orthology
Total 64 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001047 core promoter binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001542 ovulation from ovarian follicle
GO:0001544 initiation of primordial ovarian follicle growth
GO:0001547 antral ovarian follicle growth
GO:0001556 oocyte maturation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006417 regulation of translation
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0034599 cellular response to oxidative stress
GO:0042593 glucose homeostasis
GO:0043525 positive regulation of neuron apoptotic process
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001766 Transcription factor, fork head
PFAM PF00250
PRINTS PR00053
PIRSF
SMART SM00339
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N4K5
UniProt Splice Variant
Entrez Gene 535530
UniGene Bt.44365
RefSeq NP_001193012
HUGO HGNC:3821
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025936 DAAA02025937 DAAA02025938 DAAA02025939 DAAA02025940 DAAA02025941 DAAA02025942
GenPept