Bos taurus Protein: MLL5
Summary
InnateDB Protein IDBP-683387.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLL5
Protein Name myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000012129
InnateDB Gene IDBG-631821 (MLL5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0046872 metal ion binding
Biological Process
GO:0002446 neutrophil mediated immunity
GO:0006306 DNA methylation
GO:0030218 erythrocyte differentiation
GO:0030854 positive regulation of granulocyte differentiation
GO:0042119 neutrophil activation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048384 retinoic acid receptor signaling pathway
GO:0051568 histone H3-K4 methylation
GO:0071300 cellular response to retinoic acid
Cellular Component
GO:0070688 MLL5-L complex
Protein Structure and Domains
PDB ID
InterPro IPR001214 SET domain
IPR001965 Zinc finger, PHD-type
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger
PFAM PF00856
PF00628
PRINTS
PIRSF
SMART SM00317
SM00249
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MFD2
UniProt Splice Variant
Entrez Gene 539121
UniGene Bt.35488
RefSeq NP_001075920
HUGO HGNC:18541
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010537
GenPept