InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TGFA

Summary

InnateDB Protein

IDBP-683435.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TGFA

Protein Name

transforming growth factor, alpha

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001037

InnateDB Gene

IDBG-631869 (TGFA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0004708	MAP kinase kinase activity
GO:0005154	epidermal growth factor receptor binding
GO:0005515	protein binding
GO:0008083	growth factor activity

Biological Process

GO:0000165	MAPK cascade
GO:0000187	activation of MAPK activity
GO:0001525	angiogenesis
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity
GO:0045840	positive regulation of mitosis
GO:0050679	positive regulation of epithelial cell proliferation
GO:0060749	mammary gland alveolus development

Cellular Component

GO:0005615	extracellular space
GO:0009986	cell surface
GO:0016323	basolateral plasma membrane
GO:0031410	cytoplasmic vesicle
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain

PFAM

PF00008

PRINTS

PIRSF

SMART

SM00181

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q7M304

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:11765

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02030415

GenPept