InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.69347

Summary

InnateDB Protein

IDBP-683503.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.69347

Protein Name

72 kDa type IV collagenase precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025657

InnateDB Gene

IDBG-631922 (BT.69347)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0001666	response to hypoxia
GO:0001955	blood vessel maturation
GO:0001957	intramembranous ossification
GO:0006508	proteolysis
GO:0007566	embryo implantation
GO:0030574	collagen catabolic process
GO:0045089	positive regulation of innate immune response
GO:0048705	skeletal system morphogenesis
GO:0060325	face morphogenesis
GO:0060346	bone trabecula formation
GO:0071230	cellular response to amino acid stimulus

Cellular Component

GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0030017	sarcomere
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000562 Fibronectin, type II, collagen-binding
IPR000585 Hemopexin-like domain
IPR001818 Peptidase M10, metallopeptidase
IPR002477 Peptidoglycan binding-like
IPR006026 Peptidase, metallopeptidase
IPR013806 Kringle-like fold
IPR018487 Hemopexin-like repeats
IPR021190 Peptidase M10A

PFAM

PF00040
PF00413
PF01471
PF00045

PRINTS

PR00138

PIRSF

SMART

SM00059
SM00235
SM00120

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt